High sensitivity CRP (HS-CRP) is a marker for inflammation detected within the coronary lumen. Inside the walls of the coronary artery, significant inflammation results in the presence of teloproteinases and other inflammatory components.
These inflammatory factors are detected with this test called HS-CRP. Studies, such as the JUPITER trial, have shown that 40% of patients with documented coronary artery disease have normal cholesterol values, yet exhibit elevated ultra-sensitive CRP levels.
Because of this, this particular test has become critical. Dr. Nanavati also measures additional tests to detect underlying inflammation—a key factor in heart attacks.
These additional tests include LP-PLA2, oxidized LDL, as well as apo-lipoprotein B and lipo-protein a. Inflammation is the primary cause of most heart attacks, which is why merely measuring cholesterol is often insufficient.
We must measure markers of coronary inflammation. Thank you.